This name highlights the fact that Epitalon is a tetrapeptide consisting of Ala-Glu-Asp-Gly (AEDG) amino acids bound through -peptide bonds (Figure 1a)
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doi: 10.1179/1351000212Y.0000000001
By adding a mixture of reduced and oxidized glutathione, your protein can sample different disulfide bond states and should end up in the correct native state, if that is the most energetically favorable (Figure 6)
Because DSIP research is largely historical and not industrially funded, it lacks standardized research protocols, making comparison across studies difficult